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Symbol
Name
ID
Ung
uracil DNA glycosylase
MGI:109352
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Decreased circulating IgA level
Decreased circulating IgG level
Increased circulating IgM level
Impaired Ig class switch recombination
Recurrent upper and lower respiratory tract infections
Lymphadenopathy
Epididymitis
Immunodeficiency
Recurrent bacterial infections
Disease(s) Associated with UNG
immunodeficiency with hyper IgM type 5

Mouse Phenotypes
enlarged thymus
enlarged spleen
spleen hyperplasia
abnormal class switch recombination
abnormal somatic hypermutation frequency
decreased IgG3 level
increased IgM level
enlarged lymph nodes
lymphoid hyperplasia
Availability Mouse Genotype
Ungtm1Tld/Ungtm1Tld

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory